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2026-03-19

2026-03-20
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Hotels in San Diego near Santa Fe Depot

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353 results

  • Bright, Spacious 4 Bd In The Heart Of Little Italy

    From US$ 1212

    223 W Date St, San Diego, Ca 92101, Usa Villa 1, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 1212
  • Lovely Studio In The Heart Of Little Italy

    From US$ 432

    223 West Date Street 3, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 432
  • Vantaggio Suites

    State Street 1736, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    Vantaggio Suites San Diego, located 1.5 km from Seaport Village Shopping Complex, features free Wi Fi throughout the venue. The property is situated 2 km from San Diego city centre and 5 km from San…

    To the hotel

    Book Now
  • Little Italy Inn - Limited Service Apart Hotel

    From US$ 114

    1736 State Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 114
  • International Travelers House Downtown San Diego - Adults Only

    230 W Cedar Street, San Diego, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    Book Now
  • 1900'S Victorian Home Sleeps 22 8Bdrm 3Bath

    From US$ 1496

    205 West Date Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 1496
  • Ith San Diego Adventure Hostel (Adults Only)

    From US$ 45

    230 W Cedars St., San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    The 2-star International Travelers House Adventure Hostel is located around a 20-minute walk from USS Midway Interactive Museum, close to Little Italy. Guests of this San Diego hostel can enjoy a sun…

    To the hotel

    price for 1 night
    Book Now From US$ 45
  • Motel 6 San Diego, CA - Downtown

    From US$ 70

    1546 2nd Ave I-5/San Diego Freeway at 6th Avenue, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    Offering a lift, a snack and drink vending machine, Motel 6-San Diego, Ca - Downtown is set at a 450-metre distance away from First Lutheran Church. This motel also includes parking.

    To the hotel

    price for 1 night
    Book Now From US$ 70
  • 1Bd Remodeled Craftsman Cottage Free Parking Heart Of Little Italy

    1668 Front Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    Book Now
  • Upscale Modern Spacious Loft In Little Italy

    1780 Kettner Boulevard, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    Book Now
  • Quaint Studio For 2 In The Heart Of Little Italy

    From US$ 277

    1762 Columbia Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 277
  • 5Bd Home With Outdoor Space In Little Italy

    From US$ 1326

    1762 Columbia St, San Diego, Ca 92101, Usa, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 1326
  • Charming 2Nd Ave Lofts In Downtown San Diego With Parking

    From US$ 372

    1525 2Nd Avenue, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    The 1-room 303 2Nd Bright Downtown Loft Apt Parking Apartment apartment is nestled in Downtown San Diego with so much to offer from live entertainment, shopping or a night out on the town…

    To the hotel

    price for 1 night
    Book Now From US$ 372
  • Cozy 1 Bedroom Casita Overflowing With Natural Light

    1764 Columbia Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    Book Now
  • 4Bd Home In The Heart Of Little Italy

    1764 Columbia Street, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    To the hotel

    Book Now
  • The Dextro Little Italy, BW Premier Collection

    From US$ 139

    1617 1St Avenue, San Diego, United States

    0.8 km to Santa Fe Depot (To the map)

    Offering an outdoor swimming pool, a restaurant and allergy friendly rooms, the 3-star Four Points By Sheraton San Diego Downtown Little Italy Hotel is located near Cabrillo Bridge. You'll be 2.1 km…

    To the hotel

    price for 1 night
    Book Now From US$ 139
  • The Italian Retreat, Little Italy

    From US$ 210

    1805 Columbia Street, San Diego, United States

    0.9 km to Santa Fe Depot (To the map)

    The 2-room Italian Retreat, Little Italy Apartment apartment is situated in Downtown San Diego with vibrant culture, history, and plenty of things to do, 2.5 km from San Diego Zoo, which is higly…

    To the hotel

    price for 1 night
    Book Now From US$ 210
  • Beautiful Loft In Little Italy Sd With Parking

    From US$ 265

    Columbia Street 1805, San Diego, United States

    0.9 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 265
  • Little Italy Modern Lofts

    From US$ 216

    1805 Columbia St, San Diego, United States

    0.9 km to Santa Fe Depot (To the map)

    Featuring a safe deposit box and parking spaces, Little Italy Modern Lofts Aparthotel can be found within 2 km from the centre of San Diego. The venue comprises 8 rooms.

    To the hotel

    price for 1 night
    Book Now From US$ 216
  • Little Italy 3Bd Home With Huge Patio & Backyard

    From US$ 618

    1824 Columbia Street, San Diego, United States

    0.9 km to Santa Fe Depot (To the map)

    To the hotel

    price for 1 night
    Book Now From US$ 618